Understanding How RNA Molecules Fold and Function
Discovery and Function of Higher-Order RNA Structure
This project helps us understand how RNA molecules fold into complex shapes and carry out their jobs inside all living cells, which is important for future medical discoveries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11120977 on NIH RePORTER |
What this research studies
RNA molecules are vital for carrying information within our cells, and they do this not only through their genetic code but also by folding into intricate structures. While we know RNA structure is incredibly important across many life forms, we still have a lot to learn about how these structures form and communicate within cells. Our lab uses straightforward experimental methods and rigorous testing in model systems to directly observe these RNA structures and their interactions. This foundational work aims to uncover new insights into how biological processes are regulated and how RNA can be targeted for new drug development.
Who could benefit from this research
Good fit: This foundational laboratory research does not directly involve patient participation at this stage.
Not a fit: Patients seeking immediate treatment options for specific conditions would not directly benefit from this basic science project.
Why it matters
Potential benefit: If successful, this research could lead to a deeper understanding of fundamental cell processes and open new avenues for designing medicines that specifically target RNA to treat diseases.
How similar studies have performed: This work builds upon prior successes in understanding RNA structure and function, while also developing novel methods for direct detection of these structures.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Weeks, Kevin M — Univ of North Carolina Chapel Hill
- Study coordinator: Weeks, Kevin M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.