Understanding how RNA is directed to specific locations in cells
Official title: High-throughput dissection of RNA localization regulatory elements
Funded at University of Colorado Denver · NIH-10993081 · Data updated 2026-11-12
This study is looking at how certain parts of RNA help it find its way to the right spots in nerve cells, which could help us understand more about how RNA works and the problems that can happen when it doesn't function properly.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | August 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $37,773 |
| NIH project number | 5F31GM151819-02 |
| Project ID | NIH-10993081 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions related to RNA dysfunction or those interested in the biological processes of RNA localization.
✕Less likely to help
Patients with conditions unrelated to RNA localization or those not affected by RNA-related disorders may not benefit from this research.
What this research studies
This research investigates the mechanisms that control the localization of RNA within cells, focusing on specific sequences in the RNA known as 'zip-codes' that are crucial for directing RNA to its proper location. By utilizing advanced techniques to analyze thousands of RNA sequences, the study aims to identify the essential elements that facilitate RNA transport, particularly in nerve cells. This work could enhance our understanding of various biological processes and diseases linked to RNA dysfunction.
Why it matters
Potential benefit: If successful, this research could lead to new insights into RNA-related diseases and potential therapeutic strategies.
How similar studies have gone: Previous research has shown promising results in understanding RNA localization, indicating that this approach has potential for significant advancements.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Moffatt, Charlie E — University of Colorado Denver
- Study coordinator: Moffatt, Charlie E
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.