Understanding how RNA functions on cell surfaces
Functional characterization of cell surface RNA biology
['FUNDING_R01'] · BOSTON CHILDREN'S HOSPITAL · NIH-10917771
This study is looking at how certain molecules on the surface of our cells help them communicate and interact with their surroundings, which could lead to new treatments for diseases like cancer.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON CHILDREN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10917771 on ClinicalTrials.gov |
What this research studies
This research investigates the role of RNA and RNA-binding proteins on the surfaces of cells, which are crucial for cell communication and interaction with their environment. The study aims to uncover how these molecules are organized and function at the cell surface, focusing on specific proteins that are known to be involved in these processes. By exploring the molecular and biochemical activities of these RNA-binding proteins, the research seeks to fill a significant gap in our understanding of cellular biology. Patients may benefit from insights gained that could lead to new therapeutic strategies for diseases involving cell communication, such as cancers.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cellular communication and signaling, particularly cancers.
Not a fit: Patients with conditions unrelated to cellular communication or those who do not have cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance cell communication and potentially improve outcomes for patients with various diseases.
How similar studies have performed: While the specific focus on glycosylated RNAs at the cell surface is relatively novel, similar approaches in studying cell surface proteins have shown promising results in understanding cell interactions.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON CHILDREN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FLYNN, RYAN ALEXANDER — BOSTON CHILDREN'S HOSPITAL
- Study coordinator: FLYNN, RYAN ALEXANDER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers