Understanding how risk factors affect brain health in older adults
Longitudinal Risk Factor Changes and Early Recognition of Cerebral Small Vessel Disease
This study is looking at how long-term health habits and conditions might affect brain health in older adults, especially in relation to small blood vessel problems and Alzheimer's disease, to help find better ways to prevent dementia and strokes.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10789177 on NIH RePORTER |
What this research studies
This research investigates the relationship between cerebral small vessel disease (CSVD) and Alzheimer's disease, focusing on how long-term exposure to risk factors influences brain health in older adults. By analyzing data from the Framingham Heart Study and using brain MRI, the study aims to identify trends in risk factors and their impact on CSVD over time. Patients will be monitored to understand how changes in their health behaviors and treatments can affect their risk of developing dementia and stroke. The goal is to enhance preventive measures for brain health in the elderly.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those with risk factors for Alzheimer's disease or other dementias.
Not a fit: Patients who are younger or do not have any risk factors for dementia or cerebrovascular diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing dementia and stroke in older adults.
How similar studies have performed: Previous research has shown promising results in understanding the impact of vascular risk factors on brain health, making this approach both relevant and potentially impactful.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Romero, Jose Rafael — Boston University Medical Campus
- Study coordinator: Romero, Jose Rafael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.