Understanding how ribosome production affects growth in organisms
Role of Nucleolus and Ribosome Biogenesis in Coordinating Organism-wide Growth
This study is looking at how tiny parts of our cells, called ribosomes, help control growth in the tiny worm C. elegans, and it aims to find out what affects ribosome production and how that impacts the worm's development.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas at Austin NIH-funded |
| Lab location | 1 site (Austin, United States) |
| Project ID | NIH-10868436 on NIH RePORTER |
What this research studies
This research investigates the role of ribosomal DNA and ribosome production in regulating growth across an entire organism. By studying the model organism C. elegans, the researchers aim to identify factors that control ribosome synthesis and how these factors influence growth at the cellular level. The study will involve genetic screening and manipulation to observe how changes in ribosome production affect development and gene expression. This research could provide insights into the fundamental processes that govern growth and development in living organisms.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with growth disorders or those interested in developmental biology.
Not a fit: Patients with conditions unrelated to growth regulation or ribosome function may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing growth-related disorders and improving developmental biology.
How similar studies have performed: Previous research has shown promising results in understanding ribosome biogenesis and its impact on cellular processes, suggesting that this approach could yield valuable insights.
Where this research is happening
Austin, United States
- University of Texas at Austin — Austin, United States (Active)
Researchers
- Principal investigator: Sarinay Cenik, Elif — University of Texas at Austin
- Study coordinator: Sarinay Cenik, Elif
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.