Understanding how ribosome assembly affects stem cell function and development.
Mechanisms regulating ribosome assembly and function in stem cells and vertebrate development.
['FUNDING_OTHER'] · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · NIH-11088151
This study is looking at how stem cells build and use tiny machines called ribosomes, which help them grow and develop properly, so we can better understand how to support healthy stem cell function.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-11088151 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms that regulate ribosome assembly and function in stem cells, which are crucial for their growth and differentiation. The study is divided into two main programs: one focuses on identifying factors that influence ribosome assembly in stem cells, while the other examines how these processes affect protein synthesis during embryonic development. By exploring these mechanisms, the research aims to uncover how ribosome function can be tailored to support specific cellular activities, which is vital for understanding stem cell biology and development.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to blood cell development or disorders affecting stem cells.
Not a fit: Patients with conditions unrelated to stem cell function or blood cell development may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into stem cell behavior and potential therapies for blood-related disorders.
How similar studies have performed: Other research has shown promising results in understanding ribosome function in various biological contexts, indicating that this approach has potential for success.
Where this research is happening
CAMBRIDGE, UNITED STATES
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CALO-VELAZQUEZ, ELIEZER — MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Study coordinator: CALO-VELAZQUEZ, ELIEZER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.