NIH-funded research R01 grant

Understanding how reward valuation relates to suicidal behavior in at-risk adolescents

Official title: Reward Valuation and Suicidal Behavior in High-Risk Adolescents

Funded at Vanderbilt University · NIH-11030786 · Data updated 2026-11-12

This study is looking at how teenagers who are getting treatment for self-harm think about rewards they can get right away versus those they have to wait for, to see if this affects their risk of suicidal behavior, and it will follow them for six months after they leave the hospital to help find ways to keep them safe.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVanderbilt University
NIH-funded
Lab location1 site (Nashville, UNITED STATES)
Project startApril 7, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$632,539
NIH project number5R01MH130364-03
Project IDNIH-11030786 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents under 17 years old who are receiving acute psychiatric treatment for self-injurious thoughts or behaviors.

Less likely to help

Patients who are not experiencing self-injurious thoughts or behaviors may not benefit from this research.

What this research studies

This research investigates the connection between how adolescents value immediate versus delayed rewards and their risk of suicidal behavior. It focuses on high-risk youth undergoing acute psychiatric treatment for self-injurious thoughts and behaviors. By examining neural processes involved in reward valuation, the study aims to identify objective predictors of suicidal behavior and potential intervention targets. Participants will be followed for six months post-discharge, a critical period for assessing risk.

Why it matters

Potential benefit: If successful, this research could lead to better identification of adolescents at risk for suicide and inform targeted interventions.

How similar studies have gone: Previous research has indicated a link between reward valuation and suicidal behavior, suggesting that this approach has potential for meaningful insights.

Where this research is happening

  • Vanderbilt University
    Nashville, United States
    Active

Researchers

  • Principal investigator: Kujawa, Autumn J — Vanderbilt University
  • Study coordinator: Kujawa, Autumn J

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.