Understanding how reward sensitivity and circadian rhythms affect the onset of bipolar disorders in teenagers.
Integrated Reward-Circadian Rhythm Model of First Onset of Bipolar Spectrum Disorders in Adolescence
This study is looking at how being extra sensitive to rewards and having irregular sleep patterns might help predict the early signs of bipolar disorder in teenagers who are at risk, so we can better understand what makes them vulnerable during this important time in their lives.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10868610 on NIH RePORTER |
What this research studies
This research investigates the relationship between reward sensitivity and circadian rhythm disruptions in adolescents at risk for bipolar spectrum disorders (BSD). It aims to determine if heightened reward responsiveness and irregular circadian patterns can predict the first onset of BSD during this critical developmental period. By integrating these two factors, the study seeks to uncover potential mechanisms that contribute to the vulnerability of adolescents to these disorders. Participants will undergo assessments to measure their reward sensitivity and circadian rhythms over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who may be experiencing symptoms related to mood disorders or have a family history of bipolar spectrum disorders.
Not a fit: Patients outside the age range of 12 to 20 or those who do not exhibit any symptoms or family history related to bipolar spectrum disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early identification and intervention strategies for adolescents at risk of developing bipolar spectrum disorders.
How similar studies have performed: Previous research has shown promising results in understanding the interplay between reward sensitivity and circadian rhythms in mood disorders, suggesting that this integrated approach could yield valuable insights.
Where this research is happening
Philadelphia, United States
- Temple Univ of the Commonwealth — Philadelphia, United States (Active)
Researchers
- Principal investigator: Alloy, Lauren Bersh — Temple Univ of the Commonwealth
- Study coordinator: Alloy, Lauren Bersh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.