Understanding how reward devaluation affects mental health

Reward Devaluation, Positive Valence System Disturbance, and Impairment

NIH-funded research New School University · NIH-10527002

This study is looking at how feeling less motivated by rewards might affect people with depression, and it aims to find ways to help improve their treatment by understanding their responses to rewarding experiences.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionNew School University NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10527002 on NIH RePORTER

What this research studies

This research investigates how the theory of reward devaluation can predict psychological distress and functioning in individuals with varying levels of mental health symptoms. By examining how people with depression may avoid rewarding experiences, the study aims to identify underlying predictors that could guide more effective treatment interventions. Participants will engage in tasks designed to assess their responses to rewards over time, providing valuable insights into the relationship between reward systems and mental health. The findings could lead to improved therapeutic strategies for those experiencing depression.

Who could benefit from this research

Good fit: Ideal candidates include individuals experiencing symptoms of depression or related psychological distress.

Not a fit: Patients who do not exhibit any symptoms of psychopathology may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better-targeted treatments for depression by understanding how reward systems influence mental health.

How similar studies have performed: Previous research has shown promise in using reward devaluation theory to understand depression, indicating that this approach has potential for significant insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.