Understanding how retinal synapses form and function
Trans-synaptic mechanism of retinal synapse formation and function
This study is looking at how certain proteins help nerve cells in the eye connect and communicate, which is really important for seeing well, and it hopes to find out more about how problems with these connections might lead to vision issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10914964 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind the formation and function of synapses in the retina, which are crucial for visual processing. It focuses on the role of cell adhesion molecules and calcium channels in establishing connections between retinal neurons. By studying specific proteins involved in synapse formation, the research aims to uncover how these proteins coordinate to ensure proper signaling in the retina. This could lead to insights into visual disorders caused by synaptic dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing visual impairments or disorders related to retinal synapse dysfunction.
Not a fit: Patients with visual impairments not related to retinal synapse formation or function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for visual disorders related to synaptic dysfunction in the retina.
How similar studies have performed: Other research has shown success in understanding synaptic mechanisms in the retina, suggesting that this approach could yield valuable insights.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Wang, Yuchen — University of Alabama at Birmingham
- Study coordinator: Wang, Yuchen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.