Understanding how retinal neurons interact with blood vessels and respond to visual stimuli
Official title: Defining Roles of Perivascular Retinal Neurons by Integrating Visual Stimuli and Vascular Tones
Funded at University of California, San Francisco · NIH-10950258 · Data updated 2026-11-12
This study is looking at how special cells in your eyes, called retinal ganglion cells, work with nearby cells like blood vessels to help your eyes process what you see, and it’s for anyone interested in understanding more about how our vision works.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 30, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $116,888 |
| NIH project number | 1K99EY036489-01 |
| Project ID | NIH-10950258 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with retinal disorders or those experiencing visual processing issues.
✕Less likely to help
Patients with no retinal conditions or those who do not experience visual processing challenges may not benefit from this research.
What this research studies
This research investigates the interactions between retinal ganglion cells (RGCs) and nearby non-neuronal cells, such as blood vessels, to understand how these relationships influence the processing of visual information. By examining how RGCs respond not only to light but also to other stimuli like temperature and vascular pressure, the study aims to uncover the mechanisms that modulate neuronal signal processing in the retina. The approach involves advanced techniques to visualize and analyze these interactions in a controlled environment, providing insights into the complex microenvironment of the retina.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating retinal diseases and improving vision.
How similar studies have gone: Previous research has shown promising results in understanding neuronal interactions in the retina, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Wang, Fei — University of California, San Francisco
- Study coordinator: Wang, Fei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.