Understanding how respiratory viruses like SARS-CoV-2 evolve and affect the immune system

CEIRR: SARS-CoV-2 Research Activities

['FUNDING_OTHER'] · UNIVERSITY OF PENNSYLVANIA · NIH-11065381

This study is looking at how respiratory viruses like SARS-CoV-2 spread and how our immune system reacts to them, so we can better understand how to protect ourselves from getting sick.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-11065381 on ClinicalTrials.gov

What this research studies

This research investigates the factors that influence the evolution, transmission, and pathogenicity of respiratory viruses, particularly SARS-CoV-2. It involves cohort studies and sampling from both humans and animals to gain insights into how these viruses spread and how the immune system responds to infections and vaccinations. By identifying the immunological factors that affect disease outcomes, the research aims to enhance our understanding of protection against these viruses.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals who have been infected with SARS-CoV-2 or are at risk of infection, as well as those involved in vaccination studies.

Not a fit: Patients who are not affected by respiratory viruses or those who have no history of COVID-19 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing and treating COVID-19 and other respiratory viral infections.

How similar studies have performed: Other research has shown success in understanding viral evolution and immune responses, making this approach promising and relevant.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.