Understanding how respiratory viruses affect asthma symptoms
Official title: Epithelial Immune Responses During Respiratory Viral Exacerbation of Asthma
Funded at University of Washington · NIH-11058421 · Data updated 2026-11-12
This study is looking at how viral infections in the lungs can make asthma symptoms worse, especially by examining how the body's immune system and lung cells work together, and it’s inviting asthma patients to help by sharing their experiences or samples to find better treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | April 25, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $1,517,172 |
| NIH project number | 5U19AI175089-03 |
| Project ID | NIH-11058421 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals with asthma, particularly those experiencing frequent exacerbations or who have not responded to standard treatments.
✕Less likely to help
Patients with asthma who have well-controlled symptoms and respond effectively to existing treatments may not benefit from this research.
What this research studies
This research investigates how lower respiratory tract viral infections trigger asthma symptoms and exacerbations. It focuses on the role of the airway epithelium and the immune response during these viral infections, particularly in patients with different types of inflammation (T2-high and non-T2). By analyzing the interactions between immune cells and airway epithelial cells, the research aims to uncover mechanisms that could lead to better treatments for asthma. Patients may be involved in providing samples or data to help understand these processes.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for asthma patients who do not respond well to current therapies.
How similar studies have gone: Previous research has shown that understanding immune responses in asthma can lead to significant advancements in treatment, suggesting this approach has potential for success.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Hallstrand, Teal S — University of Washington
- Study coordinator: Hallstrand, Teal S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.