Understanding how respiratory glands contribute to sinusitis
Defining the role of respiratory gland patterning in rhinosinusitis
['FUNDING_OTHER'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10911119
This study is looking at how certain glands in the nose might contribute to rhinosinusitis, especially in people with cystic fibrosis, to help find better treatments for this common condition.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10911119 on ClinicalTrials.gov |
What this research studies
This research investigates the role of submucosal glands in the development of rhinosinusitis, a common airway disease affecting many individuals. By examining how these glands develop and function, particularly in patients with cystic fibrosis, the study aims to uncover the underlying causes of chronic rhinosinusitis. The research employs advanced techniques, including transcriptomic analysis and 3D imaging, to analyze gland morphology and cellular behavior. This could lead to new insights into potential treatments for those suffering from this debilitating condition.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults with chronic rhinosinusitis, particularly those with cystic fibrosis.
Not a fit: Patients with acute rhinosinusitis or those without any respiratory conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments or preventative strategies for chronic rhinosinusitis.
How similar studies have performed: Similar research has shown promise in understanding glandular function in respiratory diseases, but this specific approach is relatively novel.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAY, ALISON — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: MAY, ALISON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Airway Disease