Understanding how resistance to ferroptosis affects radiation treatment outcomes
Ferroptosis resistance as a key driver in acquired radiation resistance
This study is looking at why some cancer cells can survive radiation therapy and hopes to find ways to make the treatment work better for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11179549 on NIH RePORTER |
What this research studies
This research investigates the role of ferroptosis resistance in the context of radiation therapy, aiming to understand how certain cancer cells can survive radiation treatment. By exploring the mechanisms behind this resistance, the study seeks to identify potential therapeutic targets that could enhance the effectiveness of radiation therapy. Patients may benefit from insights gained through this research, which could lead to improved treatment strategies for those undergoing radiation therapy for cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who are undergoing or have undergone radiation therapy.
Not a fit: Patients who are not receiving radiation therapy or those with conditions unrelated to cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective radiation treatments for cancer patients, potentially improving their survival rates.
How similar studies have performed: While the specific approach of targeting ferroptosis resistance in radiation therapy is relatively novel, there is growing interest in understanding cell death mechanisms in cancer treatment, suggesting potential for success.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Gan, Boyi — University of Tx Md Anderson Can Ctr
- Study coordinator: Gan, Boyi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.