Understanding how resilience and risk factors affect cognitive health in older adults
Project 2: Aging Healthy Together: Precision Profiles of Resilience and Risk
This study is looking at how certain health markers related to heart health, blood sugar, inflammation, and the immune system can help us understand how well older adults think and remember, and it involves 1,620 people aged 50 to 79 to find out what really matters for keeping our minds sharp as we age.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-10906882 on NIH RePORTER |
What this research studies
This research investigates how various biomarkers related to cardiovascular health, glucose regulation, inflammation, and immune function can predict cognitive performance in older adults. By analyzing data from 1,620 participants aged 50 to 79 across multiple clinical sites, the study aims to identify which profiles of risk and resilience are most significant for cognitive functioning. The research also explores how these factors may be influenced by brain imaging techniques, providing a comprehensive view of cognitive health in diverse populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 50 to 79, particularly those from Hispanic/Latino, non-Hispanic Black, and non-Hispanic White backgrounds.
Not a fit: Patients outside the age range of 50 to 79 or those without concerns related to cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized strategies for maintaining cognitive health and preventing decline in older adults.
How similar studies have performed: Previous research has shown promise in using biomarkers to predict cognitive decline, making this approach both relevant and potentially impactful.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Ryan, Lee — University of Arizona
- Study coordinator: Ryan, Lee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.