Understanding how regulatory DNA controls gene expression
Multiscale genomic decryption of regulatory DNA
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10624086
This study is looking at how certain parts of our DNA work together with proteins to control how genes are turned on and off, which is important for how our cells grow and respond to different signals.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10624086 on ClinicalTrials.gov |
What this research studies
This research investigates the complex interactions of regulatory DNA and transcription factors that dictate how genes are expressed in response to various developmental signals. By employing both experimental and computational methods, the team aims to decode the organization and function of regulatory elements in the genome. This work will enhance our understanding of how multiple regulatory sites work together to influence gene activity, which is crucial for proper cellular function and response to stimuli.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with genetic disorders or conditions linked to gene expression abnormalities.
Not a fit: Patients with conditions unrelated to genetic regulation or those not affected by gene expression issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for diagnosing and treating genetic disorders by providing insights into gene regulation.
How similar studies have performed: Previous research has shown promising results in understanding gene regulation through similar experimental and computational approaches.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BENNER, CHRISTOPHER W — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: BENNER, CHRISTOPHER W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.