Understanding how Reelin affects cocaine responses in the brain
Reelin Signaling and Function in Cocaine Response
['FUNDING_R01'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-11080254
This study is looking at how a protein called Reelin affects the way cocaine impacts the brain and behavior, with the hope of finding new ways to help people struggling with cocaine addiction.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded) |
| Locations | 1 site (BIRMINGHAM, UNITED STATES) |
| Trial ID | NIH-11080254 on ClinicalTrials.gov |
What this research studies
This research investigates the role of Reelin, a protein involved in brain signaling, in the effects of cocaine on behavior and brain function. It focuses on how cocaine alters the signaling pathways in specific brain cells that are linked to addiction. By studying these changes, the research aims to uncover new insights into the biological mechanisms behind cocaine addiction and potentially identify new therapeutic targets. Patients may benefit from findings that could lead to better treatment options for stimulant abuse disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with cocaine addiction or those at risk of developing stimulant abuse disorders.
Not a fit: Patients who do not use cocaine or are not affected by stimulant abuse disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating cocaine addiction.
How similar studies have performed: While the specific role of Reelin in cocaine response has not been extensively studied, similar research approaches have shown promise in understanding addiction mechanisms.
Where this research is happening
BIRMINGHAM, UNITED STATES
- UNIVERSITY OF ALABAMA AT BIRMINGHAM — BIRMINGHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DAY, JEREMY J — UNIVERSITY OF ALABAMA AT BIRMINGHAM
- Study coordinator: DAY, JEREMY J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: addictive disorder