Understanding how REDD1 affects heart health in diabetes
Official title: Investigating REDD1 as a mediator of cardiac insulin resistance
Funded at Virginia Polytechnic Inst and St Univ · NIH-10902616 · Data updated 2026-11-12
This study is looking at how a gene called REDD1 affects the connection between type II diabetes and heart disease, with the goal of finding new ways to help people with diabetes have healthier hearts.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Polytechnic Inst and St Univ NIH-funded |
| Lab location | 1 site (Blacksburg, United States) |
| Project start | September 10, 2024 |
| Project end | September 9, 2027 |
| Funding year | 2024 |
| Award (this year) | $42,503 |
| NIH project number | 1F31HL174075-01 |
| Project ID | NIH-10902616 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults with type II diabetes who are at risk of developing cardiovascular disease.
✕Less likely to help
Patients without diabetes or those with other unrelated cardiovascular conditions may not benefit from this research.
What this research studies
This research investigates the role of a specific gene, REDD1, in the relationship between type II diabetes and heart disease. It aims to uncover how REDD1 influences insulin signaling in heart cells, which is crucial for maintaining heart health in diabetic patients. By using advanced genetic techniques, the study seeks to identify new therapeutic targets that could improve insulin sensitivity and reduce the risk of heart disease in individuals with diabetes. Patients may benefit from insights that could lead to better treatment options for diabetic cardiomyopathy.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve heart health for patients with diabetes.
How similar studies have gone: Previous research has shown promising results in understanding the role of insulin signaling in heart disease, making this approach both relevant and potentially impactful.
Where this research is happening
-
Virginia Polytechnic Inst and St Univ
Blacksburg, United States Active
Researchers
- Principal investigator: Wheeler, Mason — Virginia Polytechnic Inst and St Univ
- Study coordinator: Wheeler, Mason
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.