Understanding how recreational cannabis laws affect opioid use and overdoses

CE24-012 - The Impact of Recreational Cannabis Legalization on Substance Use Outcomes

NIH-funded research Northwestern University · NIH-11169655

This project looks at how legalizing recreational cannabis changes opioid use and overdose rates across the United States.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11169655 on NIH RePORTER

What this research studies

We want to understand if and how changes in cannabis laws influence how people manage pain with substances, especially opioids. Our team will use information from national surveys about drug use and combine it with nationwide data on overdoses. This helps us see if non-fatal and fatal overdoses change after recreational cannabis becomes legal. We will also explore if these effects differ based on specific policy details or individual backgrounds, providing important insights for public health.

Who could benefit from this research

Good fit: This research is relevant to individuals who use opioids for pain management or those at risk of opioid overdose, as it examines broad policy impacts on substance use behaviors.

Not a fit: Patients not impacted by recreational cannabis policies or opioid use may not directly benefit from this specific policy-focused research.

Why it matters

Potential benefit: If successful, this work could help policymakers create better public health strategies to address substance use and overdoses, potentially saving lives.

How similar studies have performed: While some studies have explored aspects of cannabis policy, this project uses rigorous statistical methods to provide a comprehensive, nationwide assessment of its impact on opioid outcomes.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.