Understanding how reactive oxygen species affect wound healing and tissue repair
Official title: ROS Signaling in Wound Healing vs Tissue Repair
Funded at Western Michigan University · NIH-11037222 · Data updated 2026-11-12
This study is looking at how certain molecules in the body, called reactive oxygen species, affect how wounds heal and how scars form, especially for people with diabetes or obesity, and it hopes to find ways to help improve healing and reduce scarring.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Western Michigan University NIH-funded |
| Lab location | 1 site (Kalamazoo, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $99,909 |
| NIH project number | 3R15GM150073-01S1 |
| Project ID | NIH-11037222 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with impaired wound healing due to diabetes, obesity, or other related conditions.
✕Less likely to help
Patients with acute injuries that heal normally without complications may not benefit from this research.
What this research studies
This research investigates the role of reactive oxygen species (ROS) in the processes of wound healing and tissue repair. It aims to clarify how ROS contribute to both healing and scarring, particularly in patients with conditions like diabetes and obesity that impair healing. By using planarians as a model organism, the study will explore different signaling pathways involved in these processes. The goal is to identify ways to manipulate ROS signaling to improve healing outcomes and reduce scarring.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients with chronic wounds and conditions that hinder healing.
How similar studies have gone: Previous research has shown that manipulating ROS signaling can influence healing processes, suggesting potential for success in this approach.
Where this research is happening
-
Western Michigan University
Kalamazoo, United States Active
Researchers
- Principal investigator: Beane, Wendy Scott — Western Michigan University
- Study coordinator: Beane, Wendy Scott
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.