Understanding how reactive oxygen species affect wound healing and tissue repair
Official title: ROS Signaling in Wound Healing vs Tissue Repair
Funded at Western Michigan University · NIH-10654242 · Data updated 2026-11-12
This study is looking at how certain molecules in the body, called reactive oxygen species, affect healing wounds, especially for people with diabetes or obesity, to find better ways to help them heal and reduce scarring.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Western Michigan University NIH-funded |
| Lab location | 1 site (Kalamazoo, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2023 |
| Award (this year) | $444,329 |
| NIH project number | 1R15GM150073-01 |
| Project ID | NIH-10654242 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals with diabetes, obesity, or other conditions that impair wound healing.
✕Less likely to help
Patients with acute injuries that heal normally without complications may not benefit from this research.
What this research studies
This research investigates the role of reactive oxygen species (ROS) in wound healing and tissue repair, particularly in patients with conditions like diabetes and obesity that complicate healing. The study aims to identify specific ROS signaling pathways that contribute to either effective healing or scar formation. By using model organisms, the researchers will explore how manipulating these pathways could improve healing outcomes. Patients may benefit from insights that could lead to new treatments for chronic wounds and fibrosis-related diseases.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for chronic wounds and enhanced tissue regeneration.
How similar studies have gone: Other research has shown promise in understanding ROS roles in healing, but this approach aims to clarify conflicting evidence and explore novel pathways.
Where this research is happening
-
Western Michigan University
Kalamazoo, United States Active
Researchers
- Principal investigator: Beane, Wendy Scott — Western Michigan University
- Study coordinator: Beane, Wendy Scott
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.