Understanding how reactive oxygen species affect cell signaling
Molecular mechanisms of cellular redox signaling
['FUNDING_OTHER'] · CORNELL UNIVERSITY · NIH-11004686
This study is looking at how certain molecules in our cells can both cause damage and help activate helpful processes, which could lead to better ways to treat conditions related to cell stress and injury.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CORNELL UNIVERSITY (nih funded) |
| Locations | 1 site (ITHACA, UNITED STATES) |
| Trial ID | NIH-11004686 on ClinicalTrials.gov |
What this research studies
This research investigates the dual roles of reactive oxygen species (ROS) in cellular processes, focusing on how they can both damage cells and activate beneficial signaling pathways. The study aims to identify specific pathways influenced by ROS through the modification of proteins, particularly cysteine and methionine residues. By characterizing these redox-signaling components, the research seeks to enhance our understanding of how cells manage oxidative stress and develop potential therapeutic strategies. Patients may benefit from insights gained about cellular responses to stress and injury.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions related to oxidative stress, such as aging-related disorders or chronic diseases.
Not a fit: Patients with conditions unrelated to oxidative stress or cellular signaling may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic approaches for diseases associated with oxidative stress and cellular damage.
How similar studies have performed: Other research has shown promise in understanding redox signaling pathways, indicating that this approach could yield significant insights.
Where this research is happening
ITHACA, UNITED STATES
- CORNELL UNIVERSITY — ITHACA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SEVIER, CAROLYN S — CORNELL UNIVERSITY
- Study coordinator: SEVIER, CAROLYN S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: cell injury