Understanding how radiation affects swallowing after cancer treatment
Mechanisms underlying radiation-induced dysphagia
This study is looking into why some people have trouble swallowing after treatment for head and neck cancer, and it hopes to find ways to help improve swallowing for those affected.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Louisville NIH-funded |
| Lab location | 1 site (Louisville, United States) |
| Project ID | NIH-10671079 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind swallowing difficulties, known as dysphagia, that occur after chemoradiation treatment for head and neck cancer. It aims to explore how radiation damages nerves and affects the brain's control of swallowing. By studying the neural pathways and sensory responses involved in swallowing, the research seeks to identify potential therapeutic targets to improve swallowing function in affected patients. The findings could lead to better management strategies for those experiencing these complications.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have undergone chemoradiation for head and neck cancer and are experiencing swallowing difficulties.
Not a fit: Patients who have not received chemoradiation treatment or do not have swallowing issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments that help patients regain their ability to swallow after cancer treatment.
How similar studies have performed: While the specific mechanisms of radiation-induced dysphagia are not well-studied, similar research in other areas has shown promise in understanding nerve damage and its effects on motor function.
Where this research is happening
Louisville, United States
- University of Louisville — Louisville, United States (Active)
Researchers
- Principal investigator: King, Suzanne N. — University of Louisville
- Study coordinator: King, Suzanne N.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.