Understanding how radiation affects rectal cancer
Molecular Characterization Trial of Irradiated Rectal Cancer
['FUNDING_OTHER'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-10930021
This study is looking at how radiotherapy affects rectal cancer by examining tissue samples and imaging from patients receiving standard treatment, so we can better understand how the tumor, healthy tissue, and the body's immune system work together during treatment.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10930021 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of radiotherapy on rectal cancer by analyzing tissue samples and imaging data from patients undergoing standard treatment. It aims to understand the interactions between the tumor, normal tissue, the microbiome, and the immune system. By collecting data before and after treatment, researchers will create a comprehensive model to correlate biological responses with clinical outcomes. This approach utilizes advanced bioinformatics to integrate various types of data for deeper insights into cancer treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with rectal cancer who are scheduled to undergo standard short course radiotherapy.
Not a fit: Patients with rectal cancer who are not receiving radiotherapy or those with advanced metastatic disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for rectal cancer patients, enhancing their outcomes and quality of life.
How similar studies have performed: Similar research approaches have shown promise in understanding cancer biology and improving treatment outcomes, indicating that this study builds on established methodologies.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOLDEN, ENCOUSE — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: GOLDEN, ENCOUSE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers