Understanding how racism affects preterm birth rates

Epigenomic Pathways from Racism to Preterm Birth

NIH-funded research Columbia University Health Sciences · NIH-11089583

This study is looking at how experiences of racism might affect the health of pregnant Black women and lead to early births, with the hope of finding ways to provide better care and support for those at risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11089583 on NIH RePORTER

What this research studies

This research investigates the link between racism and preterm birth, particularly focusing on non-Hispanic Black women who are disproportionately affected. By examining epigenetic changes, the study aims to uncover how experiences of discrimination may influence gene expression and contribute to adverse birth outcomes. Utilizing a large cohort of pregnant women, the research will analyze existing data, including maternal DNA and reported experiences of discrimination, to identify high-risk individuals for better prenatal care. The goal is to enhance understanding of the biological mechanisms behind preterm birth and improve prevention strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are non-Hispanic Black women who are pregnant or planning to become pregnant.

Not a fit: Patients who are not pregnant or do not identify as non-Hispanic Black may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prenatal care and targeted interventions for at-risk women, ultimately reducing preterm birth rates.

How similar studies have performed: While the link between racism and health outcomes has been explored, this specific approach using epigenomics in a diverse cohort is relatively novel and has not been extensively tested.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.