Understanding how rabbit sperm centrioles function
Official title: The Role of Rabbit POC1B inSperm Centrioles
Funded at University of Toledo · NIH-10578061 · Data updated 2026-11-12
This study looks at how tiny structures called centrioles in rabbit sperm change during their development, which might help improve sperm movement and function, and it aims to find new ways to understand and treat male infertility for couples trying to conceive.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Toledo NIH-funded |
| Lab location | 1 site (Toledo, United States) |
| Project start | June 1, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $451,500 |
| NIH project number | 1R15HD110863-01 |
| Project ID | NIH-10578061 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men experiencing infertility or difficulties in conceiving.
✕Less likely to help
Patients who are not experiencing male infertility or have other unrelated reproductive health issues may not benefit from this research.
What this research studies
This research investigates the role of centrioles in rabbit sperm and how their structure changes during sperm formation. The study focuses on a process called centriole remodeling, which may enhance sperm movement and functionality. By examining the proteins involved and their effects on fertilization, the research aims to uncover new insights into male infertility. This could lead to better understanding and potential treatments for couples facing challenges in conceiving.
Why it matters
Potential benefit: If successful, this research could provide new strategies for treating male infertility and improving reproductive health.
How similar studies have gone: While the specific focus on centriole remodeling in rabbits is novel, related research on sperm functionality has shown promising results in other species.
Where this research is happening
-
University of Toledo
Toledo, United States Active
Researchers
- Principal investigator: Avidor-Reiss, Tomer — University of Toledo
- Study coordinator: Avidor-Reiss, Tomer
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.