Understanding how pulmonary fibrosis progresses over time
Reconceptualizing Disease Progression in Pulmonary Fibrosis
This study is looking at how pulmonary fibrosis, a serious lung disease, develops in people who have symptoms and in their family members who might be at risk, to help find ways to catch the disease early and improve treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11105662 on NIH RePORTER |
What this research studies
This research investigates the progression of pulmonary fibrosis, a serious lung disease, by examining both symptomatic patients and their asymptomatic relatives who are at risk of developing the condition. The study utilizes a registry to collect data on lung function over time, employing advanced statistical methods to analyze how disease progression varies among individuals. By focusing on early detection and understanding the timeline of lung function decline, the research aims to identify better endpoints for clinical trials and improve treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with pulmonary fibrosis and their asymptomatic relatives who may be at risk for the disease.
Not a fit: Patients with other unrelated lung conditions or those who are not related to individuals with pulmonary fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and earlier interventions for patients with pulmonary fibrosis.
How similar studies have performed: Previous research has shown promise in using similar approaches to understand disease progression in other chronic conditions, suggesting potential for success in this area as well.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Salisbury, Margaret Louise — Vanderbilt University Medical Center
- Study coordinator: Salisbury, Margaret Louise
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.