Understanding how puberty affects migraines in adolescents
Official title: Migraine Prognosis in Adolescents
Funded at Washington University · NIH-10981169 · Data updated 2026-11-12
This study is looking at how different things, like hormones and emotions, affect migraines in kids aged 10 to 13 during puberty, to help us understand why their headaches might change over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $600,878 |
| NIH project number | 1R01NS134986-01A1 |
| Project ID | NIH-10981169 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 10 to 13 who have been diagnosed with episodic migraines.
✕Less likely to help
Patients outside the age range of 10 to 13 or those without a history of episodic migraines may not benefit from this research.
What this research studies
This research investigates the factors that influence migraine prognosis in adolescents, particularly during puberty. It aims to identify baseline characteristics that predict changes in headache frequency, as well as hormonal, neural, and psychological changes associated with these variations. By examining the relationships between these factors, the study seeks to improve our understanding of how migraines evolve in young people. Participants will include adolescents aged 10 to 13 who have experienced episodic migraines for more than six months.
Why it matters
Potential benefit: If successful, this research could lead to better predictions and management strategies for migraines in adolescents, improving their quality of life.
How similar studies have gone: Preliminary data suggest that similar approaches have shown promise in predicting migraine outcomes based on hormonal and neural factors.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Nahman-Averbuch, Hadas — Washington University
- Study coordinator: Nahman-Averbuch, Hadas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.