Understanding how puberty affects migraines in adolescents

Migraine Prognosis in Adolescents

NIH-funded research Washington University · NIH-10981169

This study is looking at how different things, like hormones and emotions, affect migraines in kids aged 10 to 13 during puberty, to help us understand why their headaches might change over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-10981169 on NIH RePORTER

What this research studies

This research investigates the factors that influence migraine prognosis in adolescents, particularly during puberty. It aims to identify baseline characteristics that predict changes in headache frequency, as well as hormonal, neural, and psychological changes associated with these variations. By examining the relationships between these factors, the study seeks to improve our understanding of how migraines evolve in young people. Participants will include adolescents aged 10 to 13 who have experienced episodic migraines for more than six months.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 10 to 13 who have been diagnosed with episodic migraines.

Not a fit: Patients outside the age range of 10 to 13 or those without a history of episodic migraines may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better predictions and management strategies for migraines in adolescents, improving their quality of life.

How similar studies have performed: Preliminary data suggest that similar approaches have shown promise in predicting migraine outcomes based on hormonal and neural factors.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.