Understanding how psychological and biological factors predict obesity treatment success

Psychological and Epigenetic Predictors of Obesity & Metabolic Disease

NIH-funded research Yale University · NIH-11051909

This study is looking at how your personality and certain biological markers can help predict how well you can lose weight and stick to a healthy lifestyle if you have obesity, with the goal of finding better ways to support you in your weight loss journey.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11051909 on NIH RePORTER

What this research studies

This research investigates how psychological traits and epigenetic markers can predict the success of lifestyle changes in individuals with obesity. It aims to identify which psychological resilience factors and biological changes may influence a person's ability to lose weight and maintain a healthy lifestyle. By analyzing these predictors, the study hopes to improve treatment strategies for obesity, which is a growing public health issue. Participants may undergo assessments that include psychological evaluations and biological sampling to understand their unique challenges in managing obesity.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults struggling with obesity who are seeking lifestyle intervention support.

Not a fit: Patients who are not experiencing obesity or those who have already undergone surgical interventions for weight loss may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective obesity treatment plans that consider both psychological and biological factors.

How similar studies have performed: Previous research has shown promise in using psychological and biological markers to predict treatment outcomes in obesity, suggesting this approach could be effective.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adult onset diabetesAdult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.