Understanding how proteins transport amino acids in cells
Kinetic mechanisms of amino acid transporters
['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-10655437
This study is looking at how certain proteins in our cells help move important nutrients like amino acids and glucose, which could help us understand diseases better and find new treatments.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10655437 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms by which specific proteins in cell membranes transport essential nutrients like amino acids and glucose. By utilizing advanced microscopy techniques, the study aims to observe the dynamic changes these proteins undergo during the transport process. This knowledge could help uncover the underlying causes of certain diseases and lead to the development of new therapies. The focus is on understanding both the structure and the movement of these proteins at a very detailed level.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that affect amino acid transport or related metabolic disorders.
Not a fit: Patients without any metabolic disorders or those not affected by amino acid transport issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diseases related to nutrient transport dysfunction.
How similar studies have performed: Previous research has shown success in understanding protein transport mechanisms, indicating that this approach has potential for significant findings.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LU, ZHE — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: LU, ZHE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.