Understanding how proteins interact within cells
Dynamics of the cellular interactome
['FUNDING_OTHER'] · UNIVERSITY OF WASHINGTON · NIH-10827467
This study is exploring how proteins work together inside our cells, which is really important for keeping us healthy, and it's using new tools to see these interactions in action, hoping to find better ways to understand and treat conditions like cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-10827467 on ClinicalTrials.gov |
What this research studies
This research investigates the dynamics of protein interactions inside living cells, which are crucial for cellular function and health. By developing innovative technologies, such as Protein Interaction Reporter (PIR) and advanced mass spectrometry methods, the researchers aim to visualize and quantify these interactions in real-time. This approach will help uncover how changes in protein interactions relate to various cellular conditions and treatments, potentially leading to new insights in cancer and other diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cancers or related conditions that may be influenced by protein interactions.
Not a fit: Patients with non-cancerous conditions or those not affected by protein interaction dynamics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating cancers and other diseases by targeting protein interactions.
How similar studies have performed: Other research has shown promise in understanding cellular interactions, but this approach with PIR technologies is relatively novel.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BRUCE, JAMES EDWARD — UNIVERSITY OF WASHINGTON
- Study coordinator: BRUCE, JAMES EDWARD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer