Understanding how proteins interact with RNA for cellular processes
Administrative Supplement for Equipment Purchase
['FUNDING_R15'] · UTAH STATE UNIVERSITY · NIH-10795516
This study is exploring how a special protein called Mtr4 helps manage and break down certain types of RNA in cells, and it's a great opportunity for students to get involved in real-life science research!
Quick facts
| Phase | ['FUNDING_R15'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UTAH STATE UNIVERSITY (nih funded) |
| Locations | 1 site (LOGAN, UNITED STATES) |
| Trial ID | NIH-10795516 on ClinicalTrials.gov |
What this research studies
This research investigates the complex processes involved in nuclear RNA processing and surveillance, focusing on the RNA helicase Mtr4 and its role in targeting and degrading specific RNA substrates. By employing biochemical, biophysical, and structural approaches, the project aims to uncover the molecular interactions between Mtr4 and other proteins, as well as the dynamics of these interactions. The research will also involve undergraduate and graduate students, providing them with hands-on experience in biomedical research.
Who could benefit from this research
Good fit: Ideal candidates for potential benefit from this research are individuals with malignancies or disorders related to RNA processing.
Not a fit: Patients with conditions unrelated to RNA processing or those not affected by malignancies may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of RNA processing, which may have implications for treating various cancers and other diseases related to RNA dysfunction.
How similar studies have performed: While the specific approach of this research may be novel, similar studies have shown success in understanding RNA processing mechanisms and their implications in disease.
Where this research is happening
LOGAN, UNITED STATES
- UTAH STATE UNIVERSITY — LOGAN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JOHNSON, SEAN J — UTAH STATE UNIVERSITY
- Study coordinator: JOHNSON, SEAN J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers