Understanding how proteins interact and form complexes
Prediction of the Structures of Protein Complexes
['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-11090399
This study is all about figuring out how proteins work together in our bodies, which can help scientists create better medicines for diseases like cancer and infections.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11090399 on ClinicalTrials.gov |
What this research studies
This research focuses on predicting the structures of protein complexes, which are crucial for understanding biological processes related to health and disease. By using advanced computational modeling techniques, the research aims to elucidate how proteins interact and change shape, which can inform the design of new drugs and therapies. The team is particularly interested in modeling protein-protein interactions and designing antibodies that can target specific antigens, which is essential for developing effective treatments for conditions like cancer and infectious diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to protein interactions, such as cancer or autoimmune diseases.
Not a fit: Patients with conditions unrelated to protein interactions or those who do not have a need for targeted therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective therapies and diagnostic tools for various diseases.
How similar studies have performed: Previous research has shown success in using computational modeling to predict protein structures, indicating that this approach has potential for significant advancements.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GRAY, JEFFREY J — JOHNS HOPKINS UNIVERSITY
- Study coordinator: GRAY, JEFFREY J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.