Understanding how proteins interact and affect health and disease
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This study is looking at how certain proteins work together in the body, which can help us understand things like blood clotting, Parkinson's disease, and how the COVID-19 virus affects our cells, with the hope of finding new treatments for these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers, the State Univ of N.j. NIH-funded |
| Lab location | 1 site (Piscataway, United States) |
| Project ID | NIH-11036458 on NIH RePORTER |
What this research studies
This research investigates the dynamics of protein interactions that can lead to either normal bodily functions or disease states. It focuses on three main areas: how proteins interact with collagen in blood clotting, the misfolding of a protein linked to Parkinson's disease, and how the spike protein of the SARS-CoV-2 virus interacts with human cells. By using advanced techniques like NMR and computational methods, the research aims to uncover the molecular details that influence these interactions and their implications for health. Patients may benefit from insights that could lead to new treatments for diseases related to these protein interactions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit include individuals affected by Parkinson's disease or COVID-19.
Not a fit: Patients with unrelated conditions or those not affected by the diseases being studied may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for diseases like Parkinson's and COVID-19.
How similar studies have performed: Other research has shown success in understanding protein interactions, particularly in the context of diseases like Alzheimer's and COVID-19, suggesting this approach has potential.
Where this research is happening
Piscataway, United States
- Rutgers, the State Univ of N.j. — Piscataway, United States (Active)
Researchers
- Principal investigator: Baum, Jean S — Rutgers, the State Univ of N.j.
- Study coordinator: Baum, Jean S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.