Understanding how proteins in the brain affect nerve function and diseases like Alzheimer's.
Analysis of Synaptic Protein Dynamics
This study is looking at how certain proteins in the brain help nerve cells communicate, which could help us understand more about Alzheimer's and other brain disorders, so we can find better ways to help patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10771118 on NIH RePORTER |
What this research studies
This research investigates the dynamics of synaptic proteins, which are essential for communication between nerve cells in the brain. By studying proteins like Munc13 and complexin, the project aims to uncover how these proteins influence synaptic function and contribute to conditions such as Alzheimer's disease and other neurodegenerative disorders. The research employs advanced biochemical techniques to analyze the molecular interactions within synapses, providing insights into their roles in both healthy and diseased states. Patients may benefit from a deeper understanding of the biological mechanisms underlying their conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals diagnosed with Alzheimer's disease or related neurodegenerative conditions.
Not a fit: Patients with non-neurodegenerative conditions or those not affected by Alzheimer's disease may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating Alzheimer's disease and other related disorders.
How similar studies have performed: Previous research has shown promising results in understanding synaptic proteins and their roles in neurodegenerative diseases, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Dittman, Jeremy Samuel — Weill Medical Coll of Cornell Univ
- Study coordinator: Dittman, Jeremy Samuel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.