Understanding how proteins help move RNA within cells
Official title: Role of Cytoskeletal Motor Proteins in Subcellular RNA Localization
Funded at Baylor College of Medicine · NIH-11159463 · Data updated 2026-11-12
This study is looking at how tiny proteins in our cells help move RNA to the right places, which is important for how our genes work and how our cells function, and it could help us understand diseases like cancer and neurodegeneration better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | August 1, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $400,000 |
| NIH project number | 5R35GM154922-02 |
| Project ID | NIH-11159463 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals affected by conditions related to RNA mislocalization, such as certain cancers or neurodegenerative diseases.
✕Less likely to help
Patients with conditions unrelated to RNA localization or those not affected by cellular transport mechanisms may not benefit from this research.
What this research studies
This research investigates the role of cytoskeletal motor proteins in the localization of RNA within cells, which is crucial for gene regulation and cellular function. By utilizing advanced RNA sequencing technology, the study aims to map where different RNA molecules are located in living human cells, providing insights into how these locations affect cellular processes. The research will explore the mechanisms that guide RNA to specific destinations, which could have implications for understanding diseases like cancer and neurodegeneration.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for targeting RNA localization in diseases, potentially improving treatment options for patients.
How similar studies have gone: Previous research has shown promising results in understanding RNA localization and its implications in cell biology, suggesting that this approach could yield significant insights.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Fazal, Furqan — Baylor College of Medicine
- Study coordinator: Fazal, Furqan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.