Understanding how proteins fold in cells and their role in Alzheimer's disease
Official title: Protein Folding in the Cell
Funded at Federation of Amer Soc for Exper Biology · NIH-11000524 · Data updated 2026-11-12
This study is all about a conference where new scientists will share and talk about the latest discoveries on how proteins fold correctly and what goes wrong when they don’t, especially in relation to diseases like Alzheimer's, with the goal of finding new ways to help treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Federation of Amer Soc for Exper Biology NIH-funded |
| Lab location | 1 site (Rockville, UNITED STATES) |
| Project start | July 3, 2024 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $47,175 |
| NIH project number | 1R13AG087679-01A1 |
| Project ID | NIH-11000524 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research are individuals affected by Alzheimer's disease or related dementias, particularly those interested in emerging treatment options.
✕Less likely to help
Patients who are not affected by Alzheimer's disease or related dementias may not receive direct benefits from this research.
What this research studies
This research focuses on a conference that brings together early career scientists to discuss the latest findings on protein folding and its implications for diseases like Alzheimer's. The conference will cover how proteins achieve their correct shapes and what happens when they misfold, which is a key factor in neurodegenerative diseases. Participants will engage in formal presentations and discussions to foster collaboration and generate new ideas for therapeutic strategies. The emphasis will be on understanding the biological processes involved in protein homeostasis and exploring potential treatments for age-related dementias.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating Alzheimer's disease and related dementias.
How similar studies have gone: Previous research has shown promise in using small molecule proteostasis regulators to address neurodegenerative diseases, indicating that this area of study has potential for significant advancements.
Where this research is happening
-
Federation of Amer Soc for Exper Biology
Rockville, United States Active
Researchers
- Principal investigator: Jakob, Ursula H. — Federation of Amer Soc for Exper Biology
- Study coordinator: Jakob, Ursula H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.