Understanding how proteins clump together in diseases
DMS/NIGMS 2: Statistical Network Models for Protein Aggregation
This study is looking at how proteins clump together, which is important for understanding diseases like Alzheimer's, and it's for anyone interested in how these processes work in our bodies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-10912451 on NIH RePORTER |
What this research studies
This research focuses on creating statistical models to better understand how proteins aggregate, which is important in various diseases like Alzheimer's. By combining techniques from mathematics and biophysical chemistry, the team aims to analyze the interactions of proteins over time. They will collect new experimental data and develop innovative modeling methods to provide insights into protein behavior. This could lead to a deeper understanding of the biological processes involved in diseases related to protein aggregation.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals affected by Alzheimer's disease or other conditions related to protein aggregation.
Not a fit: Patients with conditions unrelated to protein aggregation or those who do not have Alzheimer's or similar diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating diseases associated with protein aggregation, such as Alzheimer's.
How similar studies have performed: Other research has shown promise in using statistical models to study protein interactions, indicating that this approach could yield valuable insights.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Butts, Carter Tribley — University of California-Irvine
- Study coordinator: Butts, Carter Tribley
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.