Understanding how protein modifications affect diseases like cancer and diabetes
Mechanism and Inhibition of Histone Modifications
['FUNDING_OTHER'] · UNIVERSITY OF GEORGIA · NIH-11013891
This study is looking at how certain proteins in our cells can affect health and diseases like cancer and diabetes, with the goal of finding new ways to treat these conditions and help patients feel better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF GEORGIA (nih funded) |
| Locations | 1 site (ATHENS, UNITED STATES) |
| Trial ID | NIH-11013891 on ClinicalTrials.gov |
What this research studies
This research investigates the role of protein methylation, specifically on arginine and lysine residues, in various cellular processes that are crucial for health and disease. By exploring how protein methyltransferases influence gene expression, metabolism, and signaling pathways, the research aims to uncover their contributions to diseases such as cancer, diabetes, and inflammation. The team will employ innovative chemical biology techniques to identify new therapeutic targets and develop potential treatments. Patients may benefit from insights gained into disease mechanisms and the development of targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with cancer, diabetes, or other related disorders influenced by protein methylation.
Not a fit: Patients with conditions unrelated to protein methylation or those not diagnosed with cancer or diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diseases like cancer and diabetes by targeting specific protein modifications.
How similar studies have performed: Previous research has shown promising results in targeting protein methyltransferases for therapeutic purposes, indicating a potential for success in this area.
Where this research is happening
ATHENS, UNITED STATES
- UNIVERSITY OF GEORGIA — ATHENS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHENG, Y. GEORGE — UNIVERSITY OF GEORGIA
- Study coordinator: ZHENG, Y. GEORGE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers