Understanding how protein methylation affects cell function and disease
Function of Protein Methylation in Chromatin and Signaling Regulation
This study is looking at how certain changes to proteins in our cells can affect important processes like cell signaling and gene activity, which might help us understand diseases like cancer better and lead to new treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11019807 on NIH RePORTER |
What this research studies
This research investigates the role of protein methylation, specifically at lysine and histidine residues, in regulating various biological processes and chromatin biology. By studying how these modifications influence cell signaling and gene expression, the research aims to uncover the mechanisms behind diseases linked to abnormal protein methylation. Patients may benefit from insights gained about how these processes contribute to cancer and other disorders, potentially leading to new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cancers or disorders associated with dysregulated protein methylation.
Not a fit: Patients with conditions unrelated to protein methylation or those not diagnosed with cancer may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for cancers and other diseases linked to protein methylation abnormalities.
How similar studies have performed: Previous research has shown promising results in understanding the role of protein modifications in disease, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Gozani, Or P. — Stanford University
- Study coordinator: Gozani, Or P.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.