Understanding how prostate cancer spreads differently in African American men
Official title: Racial Disparities in the Mechanisms of Prostate Cancer Metastasis
Funded at Emory University · NIH-11029704 · Data updated 2026-11-12
This study is looking into why African American men are more likely to die from prostate cancer than European American men, by exploring how certain genes affect the way cancer spreads, with the hope of finding better treatments that are more suited to different genetic backgrounds.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | January 1, 2025 |
| Project end | December 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $659,498 |
| NIH project number | 1R01CA295722-01 |
| Project ID | NIH-11029704 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are African American men diagnosed with prostate cancer.
✕Less likely to help
Patients who are not African American or do not have prostate cancer may not receive direct benefits from this research.
What this research studies
This research investigates the reasons behind the higher rates of prostate cancer deaths in African American men compared to European American men. It focuses on the biological mechanisms of cancer metastasis, particularly how certain genes and signaling pathways are involved in the spread of cancer. By analyzing tumor samples and genetic data, the study aims to uncover specific genetic differences that may contribute to these disparities. Patients may benefit from insights that could lead to more effective treatments tailored to their genetic backgrounds.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for prostate cancer that are specifically designed for African American men.
How similar studies have gone: Previous research has shown that understanding genetic differences in cancer can lead to significant advancements in treatment, suggesting this approach has potential for success.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Moreno, Carlos Sanchez — Emory University
- Study coordinator: Moreno, Carlos Sanchez
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.