Understanding how prostate cancer spreads differently in African American men

Racial Disparities in the Mechanisms of Prostate Cancer Metastasis

['FUNDING_R01'] · EMORY UNIVERSITY · NIH-11029704

This study is looking into why African American men are more likely to die from prostate cancer than European American men, by exploring how certain genes affect the way cancer spreads, with the hope of finding better treatments that are more suited to different genetic backgrounds.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorEMORY UNIVERSITY (nih funded)
Locations1 site (ATLANTA, UNITED STATES)
Trial IDNIH-11029704 on ClinicalTrials.gov

What this research studies

This research investigates the reasons behind the higher rates of prostate cancer deaths in African American men compared to European American men. It focuses on the biological mechanisms of cancer metastasis, particularly how certain genes and signaling pathways are involved in the spread of cancer. By analyzing tumor samples and genetic data, the study aims to uncover specific genetic differences that may contribute to these disparities. Patients may benefit from insights that could lead to more effective treatments tailored to their genetic backgrounds.

Who could benefit from this research

Good fit: Ideal candidates for this research are African American men diagnosed with prostate cancer.

Not a fit: Patients who are not African American or do not have prostate cancer may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for prostate cancer that are specifically designed for African American men.

How similar studies have performed: Previous research has shown that understanding genetic differences in cancer can lead to significant advancements in treatment, suggesting this approach has potential for success.

Where this research is happening

ATLANTA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.