Understanding how primate retinal cells work and change with age
Structure and Function of Primate Retinal Circuits
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA BERKELEY · NIH-10747341
This study is looking at how certain cells in the eye respond to light and change as we age or develop eye diseases, with the hope of finding better ways to understand and treat vision problems.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA BERKELEY (nih funded) |
| Locations | 1 site (BERKELEY, UNITED STATES) |
| Trial ID | NIH-10747341 on ClinicalTrials.gov |
What this research studies
This research investigates the structure and function of retinal cells in primates, focusing on how these cells respond to light and how they change with aging and disease. Using advanced techniques like two-photon calcium imaging, the researchers will classify and analyze specific types of retinal cells, including ganglion and amacrine cells. The goal is to uncover how these cells interact and contribute to visual processing in different parts of the retina, particularly in the fovea and peripheral regions. This comprehensive approach aims to provide insights that could lead to better understanding and treatment of retinal disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing age-related vision changes or retinal disorders.
Not a fit: Patients with non-retinal related vision issues or those without any retinal conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for retinal diseases and age-related vision loss.
How similar studies have performed: Similar research approaches have shown promise in understanding retinal function, but this specific investigation aims to provide novel insights into primate retinal circuits.
Where this research is happening
BERKELEY, UNITED STATES
- UNIVERSITY OF CALIFORNIA BERKELEY — BERKELEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PUTHUSSERY, TERESA — UNIVERSITY OF CALIFORNIA BERKELEY
- Study coordinator: PUTHUSSERY, TERESA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.