NIH-funded research R01 grant

Understanding how prenatal stress shapes birth outcomes and early development

Official title: Advancing understanding of health disparities beginning before birth: A multisite study

Funded at Georgia State University · NIH-11384249 · Data updated 2026-11-12

This project looks at how stress during pregnancy affects a baby’s health from the womb through early infancy, with daily tracking and newborn assessments.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorgia State University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startSeptember 7, 2022
Project endJune 30, 2027
Funding year2026
Award (this year)$662,179
NIH project number5R01HD107016-05
Project IDNIH-11384249 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant individuals in the 2nd or 3rd trimester who are willing to complete daily stress diaries and participate in pregnancy and newborn assessments.

Less likely to help

Pregnant people who do not experience stress-related concerns or who are unable to participate in the required daily diaries and newborn measures may receive no direct benefit.

What this research studies

The study follows pregnant people in their 2nd and 3rd trimesters and collects daily stress information over 14 days to see how stress exposure relates to both mother and baby's physiology. It also measures maternal heart health signals during the third trimester and evaluates newborn neurodevelopment within 48 hours after birth. By including qualitative interviews, the research centers pregnant women’s lived experiences to understand buffering factors like partner support. The goal is to uncover how prenatal stress contributes to health disparities in birth outcomes and early development, informing future interventions.

Why it matters

Potential benefit: If successful, the research could lead to better screening for stress-related risks during pregnancy and new strategies to support healthier birth outcomes and early child development.

How similar studies have gone: Previous work shows associations between prenatal stress and adverse outcomes, but this study adds daily measures and qualitative context to better understand mechanisms.

Where this research is happening

  • Georgia State University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Carter, Sierra E — Georgia State University
  • Study coordinator: Carter, Sierra E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.