Understanding how prenatal HIV exposure and early life environment affect infant development in Malawi

Dissecting the causal impact of prenatal HIV exposure and the postnatal environment on development in Malawian Infants

NIH-funded research University of Maryland Baltimore · NIH-10875552

This study is looking at how being exposed to HIV before birth and the environment after birth affects the health and development of babies in Malawi, so we can find better ways to help infants who might be at risk.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Maryland Baltimore NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10875552 on NIH RePORTER

What this research studies

This research investigates how prenatal exposure to HIV and the postnatal environment influence the health and neurodevelopment of infants in Malawi. By following a cohort of infants, some exposed to HIV and some not, the study aims to identify the independent effects of these factors on child development. The research employs a multidisciplinary approach, utilizing advanced statistical methods to analyze both biological and psychosocial influences on health outcomes. This work is crucial for developing targeted interventions to improve the health of infants at risk.

Who could benefit from this research

Good fit: Ideal candidates for this research include infants born to mothers who were enrolled in the study during their second trimester of pregnancy, particularly those in Malawi.

Not a fit: Patients who are not infants or those who are not exposed to prenatal HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for enhancing the health and development of infants exposed to HIV.

How similar studies have performed: Previous research has shown success in understanding the impacts of prenatal exposures on child development, making this approach both relevant and promising.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.