Understanding how prenatal experiences affect child brain development
4/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium
['FUNDING_U01'] · CINCINNATI CHILDRENS HOSP MED CTR · NIH-10877839
This study is looking at how being exposed to substances like opioids before birth affects children's brain development as they grow up, and it's designed for families who may have experienced these risks.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CINCINNATI CHILDRENS HOSP MED CTR (nih funded) |
| Locations | 1 site (CINCINNATI, UNITED STATES) |
| Trial ID | NIH-10877839 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of prenatal exposure to substances like opioids on brain development in children from birth through childhood. By utilizing advanced neuroimaging techniques, the study aims to identify how various biological and environmental factors influence cognitive, emotional, and social development in children. The research involves collaboration among six prominent medical centers, focusing on high-risk populations to provide a comprehensive understanding of brain development trajectories. Participants will be monitored over time to assess the long-term effects of prenatal exposures.
Who could benefit from this research
Good fit: Ideal candidates for participation include pregnant women who have been exposed to opioids or other substances, as well as their children.
Not a fit: Patients who are not pregnant or whose children are not exposed to substances during pregnancy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and interventions for children affected by prenatal substance exposure.
How similar studies have performed: Previous research has shown promising results in understanding brain development through neuroimaging, but this study aims to expand on those findings with a larger, more diverse population.
Where this research is happening
CINCINNATI, UNITED STATES
- CINCINNATI CHILDRENS HOSP MED CTR — CINCINNATI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MERHAR, STEPHANIE L — CINCINNATI CHILDRENS HOSP MED CTR
- Study coordinator: MERHAR, STEPHANIE L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.