Understanding how prenatal alcohol exposure affects brain cell growth in adults
Network mechanisms of impaired adult hippocampal neurogenesis in a mouse model of prenatal alcohol exposure
This study looks at how drinking alcohol during pregnancy affects the growth of new brain cells in adults, especially in an area important for memory and learning, and it aims to find ways to help improve brain function for those affected by fetal alcohol spectrum disorder (FASD).
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Mexico Health Scis Ctr NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project ID | NIH-10893495 on NIH RePORTER |
What this research studies
This research investigates how prenatal alcohol exposure impacts the growth of new brain cells in adults, specifically focusing on the hippocampus, a region critical for memory and learning. Using a mouse model, the study examines the effects of environmental factors on neurogenesis and aims to identify potential therapeutic strategies to restore normal brain function. The researchers will explore genetic and pharmacological interventions to enhance neurogenesis and improve behavioral outcomes related to fetal alcohol spectrum disorder (FASD).
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with fetal alcohol spectrum disorder or those who have experienced prenatal alcohol exposure.
Not a fit: Patients without a history of prenatal alcohol exposure or those not affected by fetal alcohol spectrum disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve cognitive and behavioral outcomes for individuals affected by fetal alcohol spectrum disorder.
How similar studies have performed: Previous research has shown promising results in using similar approaches to enhance neurogenesis and improve cognitive function in animal models, indicating potential for success in this area.
Where this research is happening
Albuquerque, United States
- University of New Mexico Health Scis Ctr — Albuquerque, United States (Active)
Researchers
- Principal investigator: Cunningham, Lee Anna — University of New Mexico Health Scis Ctr
- Study coordinator: Cunningham, Lee Anna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.