Understanding how pregnancy-related high blood pressure affects future heart health in women
Official title: Hypertensive Disorders of Pregnancy: Pathways to Future Cardiovascular Disease
Funded at The Christ Hospital · NIH-10898886 · Data updated 2026-11-12
This study is looking at how high blood pressure problems during pregnancy, like gestational hypertension and preeclampsia, might affect a woman's heart health later on, especially by exploring how stress during pregnancy can make existing health issues worse, so we can find better ways to prevent and treat heart disease in women who have experienced these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | The Christ Hospital NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project start | May 4, 2020 |
| Project end | August 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $161,811 |
| NIH project number | 5K23HL151867-06 |
| Project ID | NIH-10898886 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who have experienced hypertensive disorders during pregnancy, such as gestational hypertension or preeclampsia.
✕Less likely to help
Patients who have not experienced any hypertensive disorders during pregnancy may not benefit from this research.
What this research studies
This research investigates the link between hypertensive disorders during pregnancy, such as gestational hypertension and preeclampsia, and the increased risk of cardiovascular diseases in women later in life. It aims to identify the underlying mechanisms that contribute to these conditions, focusing on how pregnancy stress may exacerbate existing metabolic and inflammatory issues in certain women. By studying the cardiovascular health of women with a history of these disorders, the research seeks to uncover patterns that could lead to better prevention and treatment strategies for future heart disease.
Why it matters
Potential benefit: If successful, this research could lead to improved screening and preventive measures for women at risk of cardiovascular disease due to pregnancy-related high blood pressure.
How similar studies have gone: Other research has indicated significant links between pregnancy-related hypertensive disorders and long-term cardiovascular risks, suggesting that this approach is grounded in established findings.
Where this research is happening
-
The Christ Hospital
Cincinnati, United States Active
Researchers
- Principal investigator: Quesada, Odayme — The Christ Hospital
- Study coordinator: Quesada, Odayme
Related research
Other NIH-funded projects on the same topics.
-
Pregnancy complications and women's long-term heart health
This project looks at whether complications during pregnancy predict higher risk of heart and blood vessel disease later in life for women.
-
Cardiovascular Risk in at-risk Hispanic women after pregnancy complications
We’re studying how pregnancy challenges in Hispanic women relate to heart and mental health later in life, to help identify who’s at higher risk and what care they might need.
-
Connecting women with pregnancy high blood pressure to heart-health care after birth
This project looks at how health care systems help or block women who had high blood pressure during pregnancy from getting heart-health care after delivery.
-
Finding women at risk for heart disease after pregnancy complications
This project uses machine learning to find which women who had pregnancy complications are most likely to develop heart disease so they can get earlier follow-up and prevention.
-
Pregnancy outcomes and heart health after pregnancy
Looks at how pregnancy problems like high blood pressure, early delivery, or having a small baby relate to hidden heart and blood vessel changes during and after pregnancy.
-
Heart and metabolic health after pregnancy complications in Puerto Rican women
This project looks at how pregnancy complications and mood during pregnancy relate to heart, diabetes, and mental health years later for Puerto Rican women.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.