Understanding how pregnancy affects the immune system for better maternal and fetal health
MOMI Clinical Core
['FUNDING_OTHER'] · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · NIH-11058429
This study is looking at how pregnancy affects a woman's immune system and how that can influence the health of both mom and baby, especially when it comes to infections like the flu and COVID-19, while also exploring how vaccines can help keep both of them healthy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-11058429 on ClinicalTrials.gov |
What this research studies
This research investigates the immune responses of pregnant women throughout their pregnancy, focusing on how these responses can impact both maternal and fetal health. By analyzing immune changes during each trimester, the study aims to identify risks associated with infections like influenza and COVID-19. The research will also explore how maternal vaccinations can enhance immunity for both mothers and their babies, potentially leading to improved health outcomes. Participants may contribute to a biobank that collects biological samples to further this understanding.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women, particularly those in their third trimester.
Not a fit: Patients who are not pregnant or those who are not in the third trimester may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccination strategies that enhance the health of both mothers and their infants during pregnancy.
How similar studies have performed: Previous research has shown that understanding maternal immunity can significantly improve health outcomes, particularly through vaccination strategies.
Where this research is happening
CAMBRIDGE, UNITED STATES
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: EDLOW, ANDREA GOLDBERG — MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Study coordinator: EDLOW, ANDREA GOLDBERG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: B pertussis infection, B. pertussis infection