Understanding how poxviruses evade the immune response
Novel Translational Control Mechanisms in Host Range Restriction of Poxvirus
This study looks at how certain viruses, called poxviruses, trick our body's defenses to survive and grow, and it aims to find new ways to help create better treatments for viral infections that could benefit patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-10906849 on NIH RePORTER |
What this research studies
This research investigates how poxviruses, which can be dangerous pathogens, manage to evade the host's immune response by manipulating the cellular machinery responsible for protein synthesis. The study focuses on the mechanisms of translational control that the host employs against viral infections and how poxviruses counteract these defenses. By exploring specific proteins involved in this process, the research aims to uncover new strategies for developing antiviral treatments. Patients may benefit from insights gained that could lead to improved therapies for viral infections.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals at risk of poxvirus infections or those with compromised immune systems.
Not a fit: Patients with viral infections not related to poxviruses may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antiviral strategies that enhance the body's ability to fight off poxvirus infections.
How similar studies have performed: Other research has shown success in understanding viral evasion mechanisms, indicating that this approach has potential for significant findings.
Where this research is happening
San Antonio, United States
- University of Texas Hlth Science Center — San Antonio, United States (Active)
Researchers
- Principal investigator: Xiang, Yan — University of Texas Hlth Science Center
- Study coordinator: Xiang, Yan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.